Meningeal hemangiopericytoma with extracranialliver and bone matastases
|L. Marinova, I. Mihaylova|
We present a rarely diagnosed vessel tumor (multiple meningeal hemangiopericytoma), pathologically and immunohistochemically resembling atypical meningioma. A partial resection of the tumor formation located in right, parietal region was performed in 2012, followed by postoperative radiotherapy to a total dose of 60Gy in the biggest brain formation, as well as whole cranial irradiation to a total dose of 12Gy. Multiple liver metastases were diagnosed two years after the initial diagnosis (2014). The pathology characteristics of extra cranial metastases of primary meningeal hemangiopericytoma was proven by a revision of the two biopsy (brain and liver), with addition of immunohistochemistry (СD34). The patient undergoes 9 courses chemotherapy – first andsecond line. Multiple bone metastases were diagnosed in 2016. The difficult pathology differential diagnosis of meningeal hemangiopericytoma, the needed treatment approach and the favorable effect of postoperative radiotherapy on the primarybrain tumor were discussed.After extensive survey of the medical literature, we didn’t find similar clinical case with primary manifestation of multiple meningeal hemangiopericytoma.
Key words: MALIGNANT MENINGEAL HEMANGIOPERICYTOMA. PATHOLOGY CHARACTERISTICS. IMMUNOHISTOCHEMISTRY. POSTOPERATIVE RADIOTHERAPY. LIVER AND BONE METASTASE