Рентгенология & Радиология, 2017, LVI 278-283

The role of PET/CT in patients with non-hodgkin‘s lymphoma

  1. Mladenov, V. Hadjiyska, B. Spassov, D. Vasileva, M. Ilcheva, D. Zlatareva, M. Nedevska


The aim of this work is to present the role of PET/CT (positron emission tomography combined with computedtomography) in patients with non-Hodgkin‘s lymphoma.Accurate diagnosis and placement are critical to the treatmentand prognosis of these diseases. With the introduction ofhybrid imaging methods in medical practice, new possibilitiesfor diagnosis and control of therapy have been discovered inpatients with neoplasms. In recent years, PET/CT has becomea method of choice in the study of patients with lymphoma.The main advantage of PET/CT over other visualizationimaging techniques is its ability to detect metabolic changesin areas related to malignancy before the structural changesbecome visible.For the study of patients, radiopharmaceuticals 18F-FDGwere used. The study is performed before, during (intranet)and after the end of chemotherapy. The Deauville five pointsystem as well as the Lugano classification for determining theeffect of therapy are used to evaluate the response.There are clinical cases with diagnostic differences in CT andPET/CT, defining the therapeutic algorithm. PET/CT has beendemonstrated in the monitoring of therapy in patients withnon-Hodgkin‘s lymphomas.