Positron Emission Tomography/Computed Tomography (18F-FDG PET/CT) in patients with colorectal carcinoma – literature review
- Mateva, I. Kostadinova
Colorectal carcinoma (CRC) is the third most common cancer worldwide. There is a tendency for increasing the incidence and the morbidity caused by CRC. Early diagnosis and adequate treatment strategy significantly increase patients’ life expectancy. The literature review shows that PET/CT has limited role in staging of patients with CRC, mainly for further specification of findings, suggesting distant metastases. Due to its high sensitivity and specificity for CRC, PET/CT is used for restaging in cases of elevated tumor markers, equivocal results from another imaging studies (local recurrence, specification of lymph nodes or liver lesions), as well as for evaluating the effect of chemotherapy. PET/CT might be useful for adjustment of the treatment methods, planning surgical interventions and radiotherapy and also evaluating their effect. In the future it is expected more data to be gathered, concerning the application of PET/CT for early assessment of different therapeutic methods and also its prognostic value.
Key words: COLORECTAL CARCINOMA. PET/CT. RESTAGING. THERAPEUTIC RESPONSE