Development of breast magnetic resonance phantom for tissue selective techniques
- Georgiev, T. Marov, V. Ivanov, G. Nakov, M. Peneva, G. Kirova
Magnetic resonance imaging is a modern method with increasing application in clinical practice to track and evaluate changes occurring after reconstructive breast surgery and augmentation mammoplasty. The specificity and complexity of the method, the variety of different technical parameters and protocol sequences compared to other imaging modalities, provides a strict quality control and standardization. The aim of the present study was to develop a magnetic resonance phantom for evaluation and analysis of reproducible tissue-selective techniques with signal cancellation from silicone, adipose tissue and water. The tasks were to provide physical and mechanical stability of the phantom and to obtain stable repeatable measurements from three different researchers with different experience. A breast phantom with separate cavities contained silicone implant, lard and saline was developed. Series of more than twenty datasets images were acquired from three researchers. Sequences performed included Ax STIR with silicone suppression and Ax STIR with water suppression using manual prescan and manual centre on the selected peak. Data were analyzed by Kolmogorov-Smirnov test, Paired Samples t-test and Pearson correlation coefficient to evaluate the correlation between researchers. A good mechanical stability of the phantom has been achieved which allows its long-term application under different conditions. Thermally and physically stable the phantom is also applicable for measurements with different magnetic fields in different clinical centers. Comparative analysis of the mean values showed that no significant statistical difference was observed between researcher 2 and 3. A statistically significant difference (p<0.05) was observed comparing the measurements of researcher 1 with the others. There is no correlation between the measurements of the three researchers. The proposed breast phantom can be used for obtaining reproducible measurements that allows implementation in clinical practice for tissue selective application. Also the phantom could help for raising technician qualification and training performing this type of sequences and significant reduction in processing time.
Key words: MAGNETIC RESONANCE. AUGMENTATION MAMMOPLASTY. TISSUE SELECTIVE TECHNIQUES. PHANTOM