Рентгенология & Радиология, 2018, LVII 218-222

Renal lesions in Tuberous sclerosis – MRI visualization

  1. Ilieva, D. Nenova, D. Zlatareva


Tuberous sclerosis complex is a genetic disorder characterized by hamartomatous lesions in multiple organs, frequently involving the kidneys. To visualize kidneys’ lesions is important as patients with Tuberous sclerosis complex develop clinically significant kidney disease and kidney-related complications. The aim of this study is to share authors experience in 3T MRI visualization of kidneys lesions in Tuberous sclerosis patients by the protocols used. MRI findings of 10 consecutive patients (6 females and 4 males) 12 to 51 years old with Tuberous sclerosis complex are analyzed. MRI examinations are performed on Siemens 3T equipment Verio. Protocols include T1W, T2, FLAIR, Diffusion, Dixon, Post contrast T1, Vibe sequences. Kidneys and lesions sizes are measured, lesions’ features assessed and staged. In eight out of ten patients with tuberous sclerosis multiple lesions bilaterally in enlarged kidneys are clearly defined with the feature of angiomyolipomas. The study confirms that angiomyolipomas are the most frequent kidneys impairment in tuberous sclerosis patients. The 3T MRI protocols used clearly visualize the heterogeneous renal lesions.