Contrast-enhanced magnetic resonance imaging on experimental models.
Part 1. Data processing using ImageJ script
- Dakova, D. Lazarova, I. Avdjieva, G. Hadjidekov, G. Zlateva, Zh. Zhelev, R. Bakalova
This study describes the algorithm for extracting contrast-enhanced signals from magnetic resonance images, using the ImageJ script – an open-source program available to researchers and specialists in imaging diagnostics. The aim of the article is to introduce readers to the program‘s capabilities. MRI was performed on experimental animals under anesthesia – healthy mice and mice with renal dysfunction, using 7.0 Tesla MRI for small animals. Image processing allows assessment of the level of functional impairment, based on changes in redox-status of renal tissues and dynamics of contrast in the kidneys.
Key words: CONTRAST-ENHANCED MRI. DATA ACQUISITION. IMAGEJ SCRIPT