Radiosurgery In Benign Tumors Of The Central Nervous System
- Georgiev, S. Lalova, V. Parvanova, I. Mihaylova, N. Gesheva,
- Balabanova, B. Antonov, K. Ormankova
Aim. Prospective analysis of patients with benign brain tumors who have performed radiosurgery in Clinic of radiotherapy. Material and method. For the period from June 2016 to August 2018, radiosurgery was performed in 20 patients with benign brain tumors. The patients are between 24 to 77 years old (mean 56.5 years). Women are 9 (45%) and 11 (55%) are men. All patients are operated and have residual tumor mass, disease progression or relapse, which are proven by MPT or CT. In two patients with pituitary adenoma was performed radiotherapy again. A total dose in radiosurgery is 8.5 Gy to 27 Gy (mean dose 16.23 Gy) realized in 1 to 3 fractions. Results. Patients were followed from 1 to 27 months (mean 11.8 months). All 20 patients are alive. One patient has acute neurological toxicity, which disappeared until the 6th month after treatment. The other 19 (95%) patients did not report acute reactions from the radiosurgery. One patient (5%) with meningioma has progression of disease with appearance of new meningiomas, in which has been performed radiosurgery again. In 13 (65%) patients were observed “pseudoprogression” in 6 months after the end of radiation therapy. In 9 (45%) of the patients were established regression on the disease. Conclusions. Stereotactic radiosurgery is a proven method for the ablative treatment of brain metastases, arteriovenous malformations and benign tumors of the central nervous system with dimensions less than 3 cm. Local tumor control is high over 90% from cases.
Key words: RADIOSURGERY. BENING TUMOR. CENTRAL NERVOUS SYSTEM