Moyamoya syndrome, arterial spin labeling, MRI findings
- Kalchev, R. Georgiev, M. Novakova, D. Ivanova, B. Balev
Moyamoya disease is characterized by a spontaneous stenosis or occlusion of cerebral arteries with particular involvement of the circle of Willis and development of an abnormal network of collateral vessels. Moyamoya syndrome correspond to moyamoya-type angiopathy associated with a large variety of underlying conditions (neurological or non-neurological), affecting usually the anterior circulation, more often with unilateral involvement. Clinical presentation is various, frequently a result of ischaemic or haemorrhagic events. Catheter angiography is the golden standard for diagnosis of MMD but is performed in limited cases because of its invasive nature. Magnetic resonance imaging could provide information on both cerebral vasculature (magnetic resonance angiography) and parenchymal changes making it a primary tool for moyamoya diagnosis. A new magnetic resonance technique is arterial spin labeling. It allows a non-invasive, non-ionizing assessment of brain perfusion without the application of exogenous contrast medium. This makes it a valuable addition to the MR examination especially in cases of moyamoya angiopathy.
Key words: MOYAMOYA. ARTERIAL SPIN LABELING. BRAIN PERFUSION. CBF. MAGNETIC RESONANCE ANGIOGRAPHY. ARTERIAL OCCLUSION