Cognitive Impairment Tests and MRI Correlations in Patients with Multiple Sclerosis
- Fileva, T. Kunchev, D. Zlatareva, V. Hadjidekov, L. Traykov
Multiple sclerosis is a chronic demyelinating disease with typical clinical presentation that includes physical disability, as well as cognitive dysfunction such as changes in complex attention, information processing speed, (episodic) memory and executive functions. The aim of our study was to investigate the correlation between the MRI findings (visual MRI atrophy rating scales, the cortical pathology) and the results of neuropsychological tests. Magnetic resonance imaging (MRI) is the main imaging modality, used for the diagnosis and the follow-up of the patients with multiple sclerosis. We used two visual MRI atrophy scales and additional sequence for the better visualization of the cortical pathology. We include four neuropsychological tests and one for the physical disability for comparison. Our results has shown that some MRI findings in patients with MS could be good predicting factor for the overall cognitive function.
Key words: MULTIPLE SCLEROSIS (MS). MAGNETIC RESONANCE IMAGING (MRI). BRAIN ATROPHY. CORTICAL LESIONS. COGNITIVE IMPAIRMENT