Potentiality of the Focused ultrasound surgery for the treatment of advanced pancreatic cancer patients
Pancreatic cancer is a quick progression disease and unfavorable prognosis. It is the sixth cause of cancer related death worldwide. Focused ultrasound surgery (FUS) using High Intensity Focused Ultrasound (HIFU) is a noninvasive procedure that can be used as a part of the complex treatment of advanced pancreatic cancer patients. The aim of this paper to present literature data on the potentiality of FUS as an innovative instrument for local treatment for patients with advanced pancreatic cancer. A nonsystematic literature review was performed using the databases of PubMed, Scopus, EMBASE and Cochrane Library to identify articles published before the 1st of September 2019 about FUS using HIFU for treatment of patients with advanced pancreatic cancer. Fifteen single center researches were identified from Europe and Asia that report their results for FUS treatment of patients with advanced pancreatic cancer. The researches include at least 20 patients and report data about the procedure, complications, local tumor control, pain and survival. The researches results worldwide show FUS to be secure and safe in the treatment of patients with advanced pancreatic cancer. Large, prospective multicenter trials about this innovative treatment are needed.
Key words: PANCREATIC CARCINOMA FOCUSED ULTRASOUND SURGERY