Influence of the Focussed ultrasound surgery at the patency of abdominal vessels in patients with locally advanced pancreatic cancer
- Dimitrov, N. Stanislavova, D. Angelov
Pancreatic carcinoma is the 5th most common malignant tumor in Bulgaria. 5-year survival rate is below 5%. Focused Ultrasound Surgery (FUS) using high intensity focused ultrasound is a non-invasive procedure that can be used in the complex treatment approach in patients with advanced pancreatic cancer. This study aims to answer the question regarding the extent to which FUS treatment can be utilized in vessel-infiltrating and vessels-narrowing cancers, and if the therapy itself can lead to changes in blood vessels. Since 15.01.2016 to 01.07.2018 year, total of 18 patients with local advanced pancreatic cancer- III/IV stage are selected for palliative treatment with FUS. In all patients before and after the procedure for assessment of vascular involvement by the tumor, contrast enhanced computed tomography was performed. An 128-slice tomograph Siemens Somatom Perspective was used. In our study, we use a standardized classification system to evaluate the vessels patency on a 5-point scale. The results of this study show that engagement (grade 0, 1 and 2) of abdominal vessels from the tumor is not a contraindication for FUS After the procedure, there were no cases of worsen vascular engagement and vessels lumen reduction observed in any of the studied patients. According to our study FUS is safe for the patency of the vessels involved by the advanced pancreatic cancer.
Key words: PANCREATIC CARCINOMA. FOCUSED ULTRASOUND SURGERY. ABDOMINAL VESSELS