Рентгенология & Радиология, 2019, LVIII 300-303

Low-dose high resolution computed tomography for assessment and surveillance of chronic complications in a clinical case of a child with cystic fibrosis

Blagovesta Angelova, Yordanka Uzunova, George Hadjidekov


Cystic fibrosis is an аutosomal recessive genetic disease that affects the exocrine function of the lungs, liver, pancreas, and small bowel resulting in progressive disability and multi-system failure. In this case we aim to present the use of low-dose high resolution computed tomography (HRCT) as a method of choice for the evaluation and monitoring of chronic pulmonary complications in children with cystic fibrosis. Due to the better spatial resolution, the method allows a precise observation and evaluation of the most common CT findings in patient with cystic fibrosis in the chronic stage such as air-trapping, bronchiectasis, mucoid plugs and others. The main disadvantage of CT is the radiation exposure requiring strict usage guidelines to be defined, especially during childhood. Two strategies can be applied. The first is to perform CT only for examinations with absolute indications and the second one is to apply modified low-dose CT protocols. It is possible to obtain the same radiological information from six pre-selected CT cuts as it is from a full pulmonary CT scan, thereby significantly reduction of radiation exposure in children who will require repeat investigations in the future саn be obtained.