Рентгенология & Радиология, 2019, LVIII 316-321

Рathohistological and immunohistochemical examination in metastasis in the intestines as the first symptom of lobular invasive carcinoma – clinical case with literature review

  1. Marinova, B. Yordanova, I. Mihaylova

Abstract.

Gastrointestinal breast cancer metastases are a rare finding. Even more rarely, they are manifested as the first symptom of unknown breast cancer. A clinical case of a 50-year-old woman with metastases in the terminal ileum, combined with multiple bone metastases from unknown invasive lobular carcinoma of the left mammary gland, is presented. Differential diagnosis between the intestinal metastases of breast cancer and a primary intestinal tumor is difficult due to unclear and heterogeneous symptoms. Making a correct diagnosis requires careful pathohistological and immunohistochemical examination by experienced pathologists. Gastrointestinal metastases are more common in patients with invasive lobular carcinoma. Complex treatment follows the principles of the primary disease. In similar cases, the prognosis is less favorable, but more favorable in cases with positive hormonal receptors.

Key words: GASROINTESTINAL METASTASES. BREAST CANCER. IMMUNOHISTOCHEMICAL EXAMINATION.

CHEMOTHERAPY. HORMONOTHERAP