|Radionuclide method for functional and structural examination of the thyroidal gland with 99mTc-pertechnetate|
The objective of the current study is the introduction of a complex radionuclide method for examination of the functional and structural condition of the thyroidal glandinto routine clinical practice.The method includes intra venal injection of 74 МВq 99mТсpertechnetate, thyroidal gland scintigraphy and precise calculation of the radio-marker accumulation in accordance with the specifi ed activity. One hundred and eighty two patients (159 women and 23 men, aged 19 to 80), suffering from various failures of the thyroidal gland, have been examined for the current study. Inorder to diagnostically examine the functional condition of the thyroidal gland, all patients have received detailed follow up of thyreo-stimulating hormone levels, free triidothyronine (FT3),free thyroxin (FT4), anti-thyroglobulin antibodies (anti-Tg-Ab) and microsomal antibodies (MAT). The accumulation of the 99mТс pertechnetate in euthyroidal conditions (117 patients) was approximately 1,06% +/- 0,42, in hyperthyroidal conditions (54 patients) it was 4,55% +/- 3,02, while in hypothyroidal conditions (11 patients) it was 0,22 +/- 0,11. The above method provides quick and precise diagnostic information, at the same also performing as a screening definition while differentiating euthyroidal of hyperthyroidal function of the thyroidal gland. Furthermore, we may define the shape, size, location and the structure of the gland, as well as themass, volume and the surface, necessary for the further medical strategy.
|Key words: 99mТС PERTECHNETATE. THYROID UPTAKE|