High thymic 18F-FDG uptake in Hodgkin disease

A case of high metabolic uptake at the thymic region  seen on a whole body PET-CT in а young patient with Hodgkin lymphoma 9 months after treatment with BEACOPP, DHAPand two stem cell infusions. High thymic 18F-FDG uptake is difficult to assess in pediatric patients and young adults. High uptake in that region may represent physiologic activity but also hyperplasia of the thymus, lymphomatous infiltration, neoplasm or metastatic diseas. Knowledge of different 18FFDG uptake patterns in these conditions is important for PETCT interpretation of the mediastinal region.