Рентгенология & Радиология, 2012, LI 345-348

Treatment and prognosis for pinealoblastoma –

case report and review article

  1. Georgiev, St. Georgieva, V. Parvanova, N. Gesheva


Abstract. Pineal parenchymal tumours in adults are rare and a treatment strategy for these malignancies has not yet been established. We are presenting a case of a 50 – year old woman with non- germinative cell pineal tumor. Because of the acute hydrocephalus an emergency endoscopic triventriculostomia has been performed. Histological sample has not been taken. Tumour markers: b-subunit of human chorionic gonadotropin and a-fetoprotein in the serum are negative. Treatment using „test-dose” radiotherapy for tumour region (26Gy) has been performed. Computed tomography (CT) control scans demonstrated that the mass in the pineal region decreased with 0.5 cm. We concluded that in this case we have a malignant less radiosensitive tumour – pinealoblastoma. We continued the treatment to the total dose of 56 Gy for the tumour and 30 Gy for the cranio – spinal region. Three-months after the end of the radiotherapy a CT scans showed 40% tumour reduction. The treatment strategy used in the presented case is considered to be a reasonable and effective option.