Рентгенология & Радиология, 2013, LII 20-28

Role of 18F-FDG PET/CT in diagnostic evaluation of secondary bone dissemination
S. Dineva, I. Kostadinova, V. Hadjideko


The tendency of modern diagnostic imaging of oncological diseases is aimed at reducing the number of different diagnostic procedures and single-step obtaining a large amount of information from one modality. This requirement is met by the hybrid imaging modalities and the benefit from their implementation in daily oncological practice is corroborated by the increasing number of this type of diagnostic centers.Cancer diseases are among the first with social ignificance of mortality and one of the ways to reduce this statistic, after prevention, is early diagnosis, accurate staging, reliable monitoring of the chosen therapy and follow-up. 18F-FDG PET/CT is a hybrid system that covers many of the shortcomings of each of its constituent parts and by monitoring the metabolism and accumulation of the glucose isotopic analogue it gives sufficiently precise information about the morphology and metabolism of the primary malignancy, loco-regional distribution and secondary deposits. The ability of hybrid technology to characterize bone metastases regardless of their morphological characteristics gives it a priority over the choice of several other complementary methods for obtaining comprehensive diagnostic information. Application of the method has already yielded results by the choice of the best treatment according to the oncologial stage and the change, if necessary, of the unsuitable therapeutic scheme.